Roaccutane Essay Example | Topics and Well Written Essays - 8000 words

Roaccutane - Essay Example The purposes of these studies and their problems were ascertained, noting down their findings. A reflective summary is included on clinical implications in the literature portion. The general finding of these studies on the dangerous side effects of isotretinoin use regarding psychiatric side effects including depression is inconclusive. The main issue raised is on the required number of subjects tested. As large as 8000 subjects would needed for a tenable methodology in research as suggested by the British Association of Dermatologists. Connected with this problem is the number of volunteers willing to be tested, considering that the drug is risky. Nevertheless, based on adverse reports, it is still recommended that prescribers follow precautions sent out by the Food and Drug Administration on this drug. The concern for knowing about whether isotretinoin and depression are linked rise from several adverse drug reaction reports (ADRs) received by health authorities, no less than the Food and Drug Administration (FDA) and the manufacturer of the drug involved. The highly published accounts of suicides committed by young people add to the ever growing need for looking into this problem. Literatures abound regarding these supposition and researches have been conducted to this end. To this day, there is much to be confirmed by way of collating these reports and coming up with a converged position. Acne, for which isotretinoin is usually taken is commonly associated with shame, embarrassment, social assertiveness, and self-confidence. Acne to an adolescent is associated with socialization, appearances in public, interaction with strangers, and even reduced employment opportunities (Tan 2004). As such, seeking treatment involves having access to the best there is. However, what is being bruited about as an excellent drug for the purpose of healing is equally, if not more, being blamed for the demise of some. It is necessary that what should heal should not also put one's health at risk. Isotretinoin has been serving a lot of good to those with acne, but has also been receiving several ADRs in the recent years (Schulte 2005). This study looks into possible links between Isotretinoin and depression. Acne Acne is a disorder of the sebaceous follicles or ducts located on the face, chest and back. They consist of sebaceous (secreting oil) glands associated with small hair follicles. (Cunliffe 1994). It is important to ensure that patients know that their acne is taken seriously and to reassure them that acne is treatable. The fact that it is a slow responding disorder should be stressed to patients (Ibid). Healey and Simpson (1994) identify three aims of treatment as to prevent scarring, limit the duration of the disease and reduce the impact of psychological stress. They emphasise that early treatment and regular review are necessary to prevent scarring. Treatment options are targeted at one or more of the four pathophysiological changes which occur in acne, blockage of the skin ducts, increased sebum

Competing Values Framework tes Research Paper Example | Topics and Well Written Essays - 1250 words

Competing Values Framework tes - Research Paper Example One of the dimensions related to organizational focus ranging from internal emphasis on staffs within an organization to the external focus that covers the outward relations of the organization. Their second dimension was concerned with differences between control and stability versus flexibility and change (Hamm 1993). The framework has other important aspects in addition to its original role as a leadership tool. It is a relevant tool for use across all levels within an organization. Scholars developed its name because initially, the four models that form as its pillars seemed to carry conflicting messages. Stakeholders desired to have adaptable, flexible, stable, and controlled organizations at the same time. Core Assumptions The Competing Values Framework consists of four quadrants. The first segment is the internal process model. This model bases on hierarchy, documentation, emphasises measurement, and management of information. The four processes are responsible for enhancing c ontrol and stability. It is essential to note that hierarchies function well when time is not an important factor and when an employee has sufficient knowledge about the requirements of the job. The second quadrant is the open systems model (O’Neill 1993). This model operates on organic system, readiness, resource acquisition and support, emphasises on adaptability, and growth. The processes do not control employees but inspires them. This efforts lead to staffs being innovative and creative. Rational goal model is the third core assumption of the Competing Values Model. The model centres on profit and emphasises on rational actions. The model has various assumptions that include a notion that proper planning and setting of goals leads to productivity and efficiency. The plan of action in this case, entails clarification of tasks, setting of objectives, and taking action. The final assumption is the human relations model (Hooijberg 996). This model puts a lot of emphasis on c ohesion and morale among employees. Motivation of employees according to the model comes from efficient training programs for employees. It considers employees as constituents of the organization existing in a common social system. The Competing Values Framework considers the four models that appear different and disjointed as a unit. They are related and interconnected. They fall under one large domain of organizational and managerial effectiveness. They are the invisible values that propel people, policies, and programs. Organizations live and die because of them. Application The Competing Values Framework applies in many areas within institutions and business organizations. It applies to individual styles, assess communication within organizations, and serves as a tool to analyse the degree of leadership. It helps in developing and building organizational culture for adoption by employees. This creates core competences necessary for success of a particular company. The human reso urces department within the organization uses its efficiency design motivational schemes, employee selection criteria, and the quality of employees (Quinn and Rohrbaugh 1983). The management of organizations can use the same to develop the best human resource practices, organizational capabilities, and develop change patterns. These developments are important when setting financial performance. The values of the framework apply across all ranks within organizati

No topic needed Speech or Presentation Example | Topics and Well Written Essays - 500 words

No topic needed - Speech or Presentation Example This is because the amount of time invested is less than the prize awarded. Unlike in the first case, the result after multiplying the probability with the prize and less the cost is a positive figure. (e) This time allocation is not equilibrium. This is for the reason that they both are equally talented but Shirley gets an added advantage by training longer than Laverne. They should have trained for equal time for the allocation to be equilibrium. (f) The allocation of 5 hours of training per week is not Nash equilibrium. This is because the payoff increases to 6 when the training time reduces to 4 and reduces 4 when the training time increases to 6. (e) The t-statistic is sort of a departure ratio of an approximated parameter from its speculative value as well as its usual error. It is normally used in theory testing, for instance in the t-test of Students, in bootstrapping, in addition to in the amplified Dickey–Fuller

Business law- Contracts and leases Essay Example | Topics and Well Written Essays - 1000 words

Business law- Contracts and leases - Essay Example Regardless of the type of business an individual runs, it is important to have an understanding of contract law as it is the key to making sound business agreements that can be enforced legally in the event of a dispute. Normally, a contract is enforced and governed by the laws of the country where it was made. In the United States of America, a contract is governed by two types of state laws, that is, the common law and the Uniform Commercial Code (UCC) (Bagley and Dauchy, 2012). Common Law Common law is a law which governs contracts for services and contracts that are not governed by the Uniform Commercial Code. Most contracts such as employment agreements, general business agreements and leases are controlled by common law. Common law contracts can either be bilateral or unilateral. However, the contracts are valid only if the three elements of common law contract formation are met. The elements of formation are offer, acceptance and consideration (Bagley and Dauchy, 2012). The Un iform Commercial Code (UCC) The uniform commercial code (UCC) governs the contracts between merchants and the sale of goods. The law was written by the National Conference of Commissioners on Uniform State Laws (NCCUSL) and the American Law Institute (ALI). It was published in 1952 to harmonize the law of sales and other commercial transactions in the United States. Although it has not been fully enacted, some provisions of the code have been adopted by all the fifty states of the US (Fullerton, 2011). Previously, the code was divided into 9 articles; however, after a number of reviews and revisions, the code is now divided into eleven articles with each giving provisions that relate to a particular area of commercial law. Article 1, gives the definitions of terms used in commercial law and the general principles that apply to the UCC. Article 2 covers all contracts pertaining to the sale of goods. Article 2A covers all transactions pertaining to leases of goods. Article 3 covers ne gotiable instruments such as checks and promissory notes. Article 4 governs bank collections of drafts and checks. Article 4A governs the transfer of funds through banks. Article 5 governs letters of credit. Article 6 governs bulk sales. Article 7 covers domestic documents of title. Article 8 covers all transactions in investment securities and article 9 applies to security interests in real property (Bagley and Dauchy, 2012). Differences between Contracts Formed Under Common Law and Contracts Governed By the Uniform Commercial Code (UCC) Although both the common law and the UCC govern contracts, the two laws differ in various ways. The first difference is that, contracts under uniform commercial code apply to various commercial issues such as sale of goods, banking and security interests whereas common law contracts deal with the sale of real estates, employment contracts, insurance, services and sale of intangible assets (Prabhat, 2011). According to the UCC, a good is any item th at is tangible and movable. Therefore, the sale of a home is not a sale of goods since the home is immovable. Also, the sale of a right to a trademark is not a sale of goods since it is not tangible (Cornell University Law School, 2005). The second difference between the two contracts is that, contracts under UCC can be modified without additional considerations as long as they are made in good faith whereas those under common law except

Pick a stance on the rights of animals based on Peter Singer's article Essay

Pick a stance on the rights of animals based on Peter Singer's article Famine - Essay Example The concept that we try to use to extract an argument for animal rights is the concept introduced by Singer that proximity does not matter. Whilst in this particular case, the proximity spoken of was geographic, .i.e., small child in neighbor’s house vis a vis a Bengali child, the proximity could also be in terms of species. In the logic of Peter Singer, animals cannot be denied rights given humans even if they are proximally different from the latter. Animal rights can find justification in theories of right that are embedded in time. It is interesting to begin this exposition by looking at the fairly recent debate between Singer and Judge Richard Posner of the United States Court of Appeals for the Seventh Circuit. At the heart of the debate was a statement made by Posner, that â€Å"human beings prefer their own. ... The statement that â€Å"human beings prefer their own† should in itself be subjected to critical scrutiny. Indeed, the phrase â€Å"preferring one’s own† denotes a value choice in favour of an entity or a construct that hews closely to how one perceives him or herself and possesses many of the same characteristics that he or she has. Indeed, the very same moral intuition that drives the argument of Posner is the same so-called moral intuition that has been the basis for the discrimination on the basis of gender (e.g., the discrimination against lesbians, gays, bisexuals and transgenders), of race (e.g., the discrimination against blacks) and of religion (e.g., the discrimination against Islam.) History has amply demonstrated the folly of taking that statement, â€Å"human beings prefer their own†, as justified and benign. The moral equality theorists argue that there must be an equal consideration of the interests of human beings and animals. Peter Singer is perhaps one of the leading lights of animal ethics. He states the principle of moral equality as follows: The essence of the Principle of Equal Consideration of Interests is that we give equal weight in our moral deliberations to the like interests of all those affected by our actions.3 The main defense for this theory is that the properties that we ascribe to humans that distinguish them from animals are not properties  that all human beings have, and thus, the logic deployed by those who distinguish humans from animals as a means to justify unequal treatment of humans and animals may give rise to a case of discrimination. For example, not all human beings are capable of rational thought – an example would be infants. Some humans have dementia or schizophrenia. Does the argument then

China's Dangerous Overvaluation Article Example | Topics and Well Written Essays - 500 words

China's Dangerous Overvaluation - Article Example Based upon labor costs and trade patterns, author is of the view that Yuan is certainly overvalued by approximately 15% suggesting that it’s time for China to take corrective measures. Author suggests measuring increasing labor costs as one of the indicators to measure how much the currency has appreciated and also cites the fact that labor costs have increased more than the overall profitability of the Chinese companies. Author indicates that any further appreciation in the currency would actually be more harmful for the country because the overall level of debt has been creeping up in the economy which would ultimately hurt the domestic consumption in China. Author suggests that to arrest the appreciation of Yuan, one way could be to allow domestic prices to adjust to the appreciated Yuan however; this may result into difficult economic consequences whereas rebalancing from investment to consumption is recommended as an easier way to manage Yuan. Probably one of the biggest weaknesses of the article is the absence of any figures and data based upon which author made the claims. Almost all the arguments are without any solid economic data and most arguments are relatively theoretical in nature. It would have been much better had the author used the real economic data to point out the appreciation trends in the value of Yuan against the major international currencies specially US Dollar. It is also critical to note that China has basically not highlighted as to how an appreciated Yuan have been benefiting Chinese economy in maintaining healthy trade surplus besides emerging as the leading export oriented economy in the world. An increase in the labor costs may not be one of the basic indicators of measuring the appreciation in Yuan. An increase in labor costs may also be due to the increasing specialization within the Chinese economy and the fact that Chinese workers may be gaining more advanced skills. Gaining more

Aquina Paper Essay Example | Topics and Well Written Essays - 500 words

Aquina Paper - Essay Example They are still important despite the overlapping with the other truths because it is vital that aside from philosophical science developed by human reason, there must be â€Å"theology† learned through divine revelation (Pojman & Vaughn 52-54). There are no justifications why such knowledge that could be learned through philosophical science, so long as it can be learned through natural reason, could not be learned through sacred science or theology either. Aquinas then explained that there are two forms of science, natural science and higher science. Sacred Doctrine is a science because it progresses from norms coming from higher science, specifically the science of God. He used the example of a musician who trusts in the teachings of a mathematician by reason of authority; the same can be said of sacred science, which is founded on knowledge from God’s revelation. He further argues that Sacred Doctrine is the noblest of sciences because it focuses on the noblest subject matter, which is God, and it offers the most graciously gratifying certainty because it expresses God’s authority. Also, Sacred Doctrine directs us to the noblest objective, which is toward eternal happiness with God. Sacred Doctrine is knowledge, which offers us the most profound and meaningful wisdom of our unending worth and guides us toward its attainment. These premises lead to a single conclusion-- therefore, an unmoved First Mover is real and existent. Whether these premises are valid, invalid, or sound require further examination. Validity is the value of being accurately, empirically, and concretely logical or justifiable; invalidity refers to a lack of factual reliability; soundness refers to the validity of the premises and conclusion. Through the Argument from Change, Aquinas illustrates that human reason has a role in Sacred doctrine not to verify or attest to the knowledge based on faith, but to shed light on â€Å"other things that are put forward in this doctrine†